Hereditary
Angiodema
Harriet Joyce Foundation Backs Genetic Research on Hereditary Angioedema in Ecuador
The Harriet Joyce Foundation (HJF) is proud to announce its support for a groundbreaking research project focused on hereditary angioedema (HAE) in Ecuador, led by Dr. Ivan Cherrez-Ojeda and supported by Respiralab. This initiative seeks to conduct whole genome sequencing (WGS) on a cohort of 34 patients from 11 families in the province of Manabí, with the goal of identifying genetic variations specific to the Ecuadorian population. These insights will help improve understanding of this rare genetic condition, characterized by painful and potentially dangerous swelling episodes, and enable the development of more precise treatment strategies.
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Advancing Global and Local Understanding of HAE
By studying the genetic basis of HAE—particularly the predominance of type II cases in Ecuador—researchers aim to uncover how specific gene variants influence disease severity, frequency, and response to treatment. According to Dr. Cherrez-Ojeda, this research holds promise not only for the families affected in Manabí but also for advancing global knowledge on HAE, potentially benefiting patients around the world. Ana Maria Pesantes, President of HJF Ecuador, emphasized the project’s significance in addressing local health challenges and improving the quality of life for those living with this condition.
A Commitment to Community Health and Collaboration
The Harriet Joyce Foundation remains dedicated to supporting impactful health initiatives that resonate with the needs of local communities. Through close collaboration with Ecuadorian medical experts and organizations like Respiralab, HJF is committed to fostering innovation in genetic research and patient care. For more information about the foundation’s work and current projects, visit